Dilantin Side Effects


Dilantin® / Phenytoin

Dilantin-125 (phenytoin) Oral Suspension Detailed View: Safety Labeling Changes Approved By FDA Center for Drug Evaluation and Research (CDER) – December 2011

... PRECAUTIONS Drug Interactions (revised) Phenytoin is extensively bound to serum plasma proteins and is prone to competitive displacement. Phenytoin is metabolized by hepatic cytochrome P450 enzymes CYP2C9 and CYP2C19, and is particularly susceptible to inhibitory drug interactions because it is subject to saturable metabolism. Inhibition of metabolism may produce significant increases in circulating phenytoin concentrations and enhance the risk of drug toxicity.

Phenytoin is a potent inducer of hepatic drug-metabolizing enzymes. Serum level determinations for phenytoin are especially helpful when possible drug interactions are suspected.


Dilantin Safety Review

Stevens-Johnson Syndrome (SJS) іѕ a condition thаt causes cell death аnd thе separation οf thе epidermis (skin) frοm thе dermis

. Whіlе іt іѕ a milder form οf Toxic Epidermal Necrolysis (TEN), іt іѕ still serious enough tο result іn ... NSAIDS:

ibuprofen,naproxen, diclofenac, valdecoxib, Barbiturates: phenobarbitol Penicillins Phenytoins (antiepileptics) аnd Anticonvulsants: dilantin, phenytek, lamotrigine, carbamazepine, ethosuximide Sulfonamides Enzyme ...

 Pittsburgh, PA: Although cases of Stevens Johnson syndrome, also known as SJS, are rare, they can have a devastating effect on patients.

Some people who developed Stevens Johnson syndrome symptoms have filed lawsuits against the makers of the drugs they say caused the condition, alleging that drugmakers failed to adequately warn about the risk of Stevens Johnson syndrome skin disease.

Now, a federal judge has ruled against Johnson & Johnson in a Stevens Johnson syndrome lawsuit.

Dilantin Seizure Treatment

Dilantin Seizure Treatment -- diphenylhydantoin: an anticonvulsant drug (trade name Dilantin) used to treat epilepsy and that is not a sedative.

Why is this Dilantin Seizure Treatment medication prescribed?  (MedlinePlus)

Phenytoin is used to treat various types of convulsions and seizures.

Phenytoin acts on the brain and nervous system in the treatment of epilepsy.

This Dilantin Seizure Treatment medication is sometimes
prescribed for other uses; ask your doctor or pharmacist for more information.

What side effects can Dilantin seizure treatment medication cause?  

Side effects from phenytoin may occur. Tell your doctor if any of these symptoms are
severe or do not go away:

  • redness, irritation, bleeding, and swelling of the gums
  • mental confusion
  • blurred or double vision

If you experience any of the following symptoms, call your doctor immediately:

  • difficulty coordinating movements
  • skin rash
  • easy bruising
  • tiny purple-colored skin spots
  • bloody nose
  • slurred speech
  • unusual bleeding
  • yellowing of the skin or eyes
  • dark urine
  • swollen glands
  • fever
  • sore throat

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone